Nuclear Medicine Imaging in Pediatric Infection or Chronic Inflammatory Diseases

In this review article, we focus on the most recent applications of nuclear medicine techniques (mainly 99mTc/111In white blood cells (WBC) scan, [18F]-FDG-PET/CT, [18F]-FDG-PET/MRI, and 99mTc-IL-2 scintigraphy) in the study of children affected by peripheral bone osteomyelitis, fungal infections, inflammatory bowel diseases, and type 1 diabetes, owing to recent important published evidences of their role in the management of these diseases. For osteomyelitis in children, both bone scintigraphy and [18F]-FDG-PET have a major advantage of assessing the whole body in one imaging session to confirm or exclude multifocal involvement, whereas WBC scan has a limited role.

Source: Seminars in Nuclear Medicine - February 9, 2017 Category: Nuclear Medicine Authors: Alberto Signore, Andor W.J.M. Glaudemans, Olivier Gheysens, Chiara Lauri, Onofrio A. Catalano Source Type: research