Abnormal Fear Circuitry in Attention Deficit Hyperactivity Disorder: A Controlled Magnetic Resonance Imaging Study

We examined whether non-traumatized subjects with Attention Deficit Hyperactivity Disorder (ADHD) have dysfunctional activation in brain structures mediating fear extinction, possibly explaining the statistical association between ADHD and other disorders characterized by aberrant fear processing such as PTSD. Medication na ïve, non-traumatized young adult subjects with (N=27) and without (N=20) ADHD underwent a 2-day fear conditioning and extinction protocol in a 3T functional magnetic resonance imaging (fMRI) scanner.

Source: Psychiatry Research: Neuroimaging - February 9, 2017 Category: Psychiatry Authors: Andrea E. Spencer, Marie-France Marin, Mohammed R. Milad, Thomas J. Spencer, Olivia E. Bogucki, Amanda L. Pope, Natalie Plasencia, Brittany Hughes, Edward F. Pace-Schott, Maura Fitzgerald, Mai Uchida, Joseph Biederman Source Type: research