Corpus callosum volumes in bipolar disorders and suicidal vulnerability

Reduced size of the corpus callosum (CC) has been associated with bipolar disorders and suicidality. Here, we aimed at investigating the relative independence of these associations in a large sample of patients. Two samples of males and females totaling 209 euthymic participants were recruited, including 72 patients with major depressive disorder, 64 with bipolar disorders and 73 healthy controls. Among patients, 61 had a history of suicide attempt and 75 had none. Structural scans were acquired with 1.5T magnetic resonance imaging.

Source: Psychiatry Research: Neuroimaging - February 9, 2017 Category: Psychiatry Authors: Anthony J. Gifuni, Emilie Oli é, Yang Ding, Fabienne Cyprien, Emmanuelle le Bars, Alain Bonafé, Philippe Courtet, Fabrice Jollant Source Type: research