Central action of xenin affects the expression of lipid metabolism-related genes and proteins in mouse white adipose tissue

Xenin is a gastrointestinal hormone that reduces food intake when administered centrally and it has been hypothesized that central action of xenin participates in the regulation of whole-body metabolism. The present study was performed to address this hypothesis by investigating the central effect of xenin on the expression of genes and proteins that are involved in the regulation of lipid metabolism in white adipose tissue (WAT). Male obese ob/ob mice received intracerebroventricular (i.c.v.) injections of xenin (5 μg) twice 12h apart.
Source: Neuropeptides - Category: Neuroscience Authors: Source Type: research