Role of NOD- like Receptors in Glioma Angiogenesis: Insights into future therapeutic interventions

Gliomas are the most prevalent solid tumors accounting for 46 –70% of all central nervous system (CNS) tumors [1]. There are more than 100 histologically distinct types of primary brain and CNS tumors. Nearly 78,000 new cases of primary brain tumors are expected to be diagnosed this year [2]. This figure includes nearly 25,000 primary malignant and 53,000 no n-malignant brain tumors [2]. There are nearly 700,000 people in the U.S. living with a primary CNS tumor [2]. These tumors can be composed of either heterogeneous or homogenous population of cells such as microglia, astrocytes and oligodendrocytes.

Source: Cytokine and Growth Factor Reviews - February 9, 2017 Category: Molecular Biology Authors: Shivanjali Saxena, Sushmita Jha Tags: Survey Source Type: research