Magnetic facial nerve stimulation in animal models of active seizure

We are developing a non-invasive facial nerve stimulator device as an emergency treatment for ischemic stroke. It is well-known that electric stimulation of the parasympathetic petrosal components of the facial nerve causes dilation of the cranial arteries and an increase in cerebral blood flow in normal animals (Forbes et al., 1937, 1939; Meyer et al., 1967; Adams et al., 1989; Goadsby, 1989, 1990a,b, 1991; Goadsby and Hoskin, 1994; Sato et al., 1997; Toda et al., 2000a,b) and in animals with brain ischemia (Yarnitsky et al., 2005, 2006; Henninger and Fisher, 2007; Takahashi et al., 2011).

Source: Epilepsy Research - February 7, 2017 Category: Neurology Authors: Mark K. Borsody, Andrea Garcia, Dawn M. Bielawski, Chisa Yamada, Emilio Sacristan Source Type: research