Dietary psyllium fiber increases intestinal heat shock protein 25 expression in mice

Heat shock proteins (HSPs) protect intestinal epithelial cell function, integrity and viability against many forms of stress. We hypothesized that dietary fibers (DFs) in the diet may increase HSP expression, since DFs are known to exhibit beneficial effects on intestinal health. The present study investigated the regulation of intestinal HSP expression by DFs, particularly psyllium fiber. Feeding psyllium fiber for 5 d increased HSP25 expression, but not HSP32 and HSP70 expression in the jejunum, ileum, and colon of mice at both the protein and mRNA levels.

Source: Nutrition Research - February 6, 2017 Category: Nutrition Authors: Miyuki Ogata, Tran Van Hung, Hiroyuki Tari, Teruaki Arakawa, Takuya Suzuki Source Type: research