Enantioseparation of methamphetamine by supercritical fluid chromatography with cellulose- based packed column

Chirality of the seized drugs of abuse can provide the valuable information for criminal investigation. For example, the proportion of enantiomers of methamphetamine (MA) is deeply related to its synthetic route and raw materials used in the clandestine laboratory. The representative starting materials of the illicitly manufactured MA are 1-phenyl-2-propanone (P2P), ephedrine (EP) and pseudoephedrine (PEP). In the case of P2P, MA can be synthesized through the reductive amination or Leuckart reaction.

Source: Forensic Science International - February 3, 2017 Category: Forensic Medicine Authors: Hiroki Segawa, Yuko T. Iwata, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Tatsuyuki Kanamori, Hiroyuki Inoue Source Type: research