WNT regulation of embryonic development likely involves pathways independent of nuclear CTNNB1

In conclusion, canonical WNT signaling is attenuated in the preimplantation bovine embryo but WNT can activate the PCP component JNK. Thus, regulation of embryonic development by WNT is likely to involve activation of pathways independent of nuclear actions of CTNNB1.

Source: Reproduction - February 2, 2017 Category: Reproduction Medicine Authors: Tribulo, P., Moss, J. I., Ozawa, M., Jiang, Z., Tian, X., Hansen, P. J. Tags: Research Source Type: research