Bone marrow evaluation for diagnosis and monitoring of acute myeloid leukemia
The diagnosis of acute myeloid leukemia (AML) can be made based on peripheral blood or bone marrow blasts. In this review, we will discuss the role of bone marrow evaluation and peripheral blood monitoring in the diagnosis, management, and follow up of AML patients. For patients with circulating blasts, it is reasonable to perform the necessary studies needed for diagnosis and risk stratification, including multiparametric flow cytometry, cytogenetics, and molecular analysis, on a peripheral blood specimen.
Source: Blood Reviews - Category: Hematology Authors: Mary-Elizabeth Percival, Catherine Lai, Elihu Estey, Christopher S. Hourigan Tags: Review Source Type: research