Cytochrome 2B6 polymorphism and efavirenz ‐induced central nervous system symptoms : a substudy of the ANRS ALIZE trial

ConclusionsThe deficient CYP2B6 516 T allele is associated with higher efavirenz plasma drug levels and more frequent CNS‐related symptoms.

Source: HIV Medicine - January 31, 2017 Category: Infectious Diseases Authors: S Gallien, V Journot, M ‐A Loriot, H Sauvageon, P Morlat, J Reynes, V Reliquet, G Chêne, J‐M Molina, Tags: Original Research Source Type: research