RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins

Nature Reviews Immunology 17, 130 (2017). doi:10.1038/nri.2016.129 Authors: Mingui Fu & Perry J. Blackshear Nearly 60 CCCH zinc finger proteins have been identified in humans and mice. These proteins are involved in the regulation of multiple steps of RNA metabolism, including mRNA splicing, polyadenylation, transportation, translation and decay. Several CCCH zinc finger proteins, such as tristetraprolin (TTP), roquin 1
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research