Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures

Nature Reviews Immunology 17, 112 (2017). doi:10.1038/nri.2016.134 Authors: Jan Felix & Savvas N. Savvides Immune responses are regulated by effector cytokines and chemokines that signal through cell surface receptors. Mammalian decoy receptors — which are typically soluble or inactive versions of cell surface receptors or soluble protein modules termed binding proteins — modulate and antagonize signalling by canonical effector–receptor
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research