Cell cycle proteins as promising targets in cancer therapy

Nature Reviews Cancer 17, 93 (2017). doi:10.1038/nrc.2016.138 Authors: Tobias Otto & Piotr Sicinski Cancer is characterized by uncontrolled tumour cell proliferation resulting from aberrant activity of various cell cycle proteins. Therefore, cell cycle regulators are considered attractive targets in cancer therapy. Intriguingly, animal models demonstrate that some of these proteins are not essential for proliferation of non-transformed cells
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research