Cell cycle proteins as promising targets in cancer therapy
Nature Reviews Cancer 17, 93 (2017).
doi:10.1038/nrc.2016.138
Authors: Tobias Otto & Piotr Sicinski
Cancer is characterized by uncontrolled tumour cell proliferation resulting from aberrant activity of various cell cycle proteins. Therefore, cell cycle regulators are considered attractive targets in cancer therapy. Intriguingly, animal models demonstrate that some of these proteins are not essential for proliferation of non-transformed cells
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tobias Otto Piotr Sicinski Tags: Review Source Type: research