Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer

Nature Reviews Cancer 17, 79 (2017). doi:10.1038/nrc.2016.126 Authors: Rodrigo Dienstmann, Louis Vermeulen, Justin Guinney, Scott Kopetz, Sabine Tejpar & Josep Tabernero Critical driver genomic events in colorectal cancer have been shown to affect the response to targeted agents that were initially developed under the 'one gene, one drug' paradigm of precision medicine. Our current knowledge of the complexity of the cancer genome, clonal evolution patterns under
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research