Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells

Conclusions Targeted inhibition of Notch1 gene may enhance the killing effects of paclitaxel on triple negative breast cancer cells by up-regulating the expression of Caspase-3 and Caspase-9 and inhibiting the expression of Bcl-2.
Source: Asian Pacific Journal of Tropical Medicine - Category: Tropical Medicine Source Type: research