Tumor necrosis factor suppresses interleukin 10 in peripheral B cells via upregulating Bcl2 ‐like protein 12 in patients with inflammatory bowel disease
In conclusion, Bcl2L12 mediates the effects of TNF to suppress the expression of IL‐10 in B cells. The data suggest that Bcl2L12 may be a therapeutic target for the treatment of IBD.
Source: Cell Biochemistry and Function - Category: Biochemistry Authors: Xiutian Guo, Mao ‐Gang Li, Shan‐Shan Li, Feng‐Hua Liu, Zhan‐Ju Liu, Ping‐Chang Yang Tags: RESEARCH ARTICLE Source Type: research