Necroptosis in development, inflammation and disease

Nature Reviews Molecular Cell Biology 18, 127 (2017).
doi:10.1038/nrm.2016.149

Authors: Ricardo Weinlich, Andrew Oberst, Helen M. Beere & Douglas R. Green
In the early 2000s, receptor-interacting serine/threonine protein kinase 1 (RIPK1), a molecule already recognized as an important regulator of cell survival, inflammation and disease, was attributed an additional function: the regulation of a novel cell death pathway that came to be known as necroptosis. Subsequently,

Source: Nature Reviews Molecular Cell Biology - December 20, 2016 Category: Cytology Authors: Ricardo Weinlich Andrew Oberst Helen M. Beere Douglas R. Green Tags: Perspectives Source Type: research