Translation: Ubiquitylation mediates quality control

Nature Reviews Molecular Cell Biology 18, 71 (2017). doi:10.1038/nrm.2017.6 Author: Eytan Zlotorynski Terminally stalled ribosomes can initiate degradation of nascent polypeptides and the dissociation of ribosome subunits, a process known as ribosome-associated quality control (RQC). Using a reporter that quantitatively measures ribosome terminal stalling, Juszkiewicz and Hegde found that most ribosomes in human cells stalled when they
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research