Development: Metabolism regulates lymphangiogenesis

Nature Reviews Molecular Cell Biology 18, 71 (2017). doi:10.1038/nrm.2017.5 Author: Kim Baumann Wong et al. report that metabolism — more specifically, fatty acid β-oxidation (FAO) — promotes lymphatic development. They found that FAO is high in lymphatic endothelial cells (LECs; which line lymph vessels) and that inhibition or LEC-specific loss of CPT1A, which is a rate-controlling
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research