Kidney Paired Exchange and Desensitization: Strategies to Transplant the Difficult to Match Kidney Patients with Living Donors

With organs in short supply, only a limited number of kidney transplants can be performed a year. Live donor donation accounts for 1/3rd of all kidney transplants performed in the United States. Unfortunately, not every donor recipient pair is feasible because of Human leukocyte antigen (HLA sensitization and ABO incompatibility. To overcome these barriers to transplant, strategies such as kidney paired donation (KPD) and desensitization have been developed. KPD is the exchange of donors between at least two incompatible donor-recipient pairs such that they are now compatible.
Source: Transplantation Reviews - Category: Transplant Surgery Authors: Source Type: research