Glycomacropeptide in children with phenylketonuria: does its phenylalanine content affect blood phenylalanine control?

ConclusionsIn the control group, there was a nonsignificant fall in phenylalanine concentrations (pre‐study, 325 μmol L−1; study, 280 μmol L−1; P = 0.9) and no significant changes for tyrosine or Phe : Tyr ratios (P = 0.9). Children taking the CGMP‐AA found it more acceptable to L‐AA. Blood phenylalanine control declined with CGMP‐AA but, by titrating the dose of CGMP‐AA, blood phenylalanine control remained within target range. The additional intake of phenylalanine may have contributed to the change in blood phenylalanine concentration. CGMP‐AA use requires careful monitoring in children.
Source: Journal of Human Nutrition and Dietetics - Category: Nutrition Authors: Tags: Research Paper Source Type: research