Key clinical milestones 15 years and onwards after DBS-STN surgery —A retrospective analysis of patients that underwent surgery between 1993 and 2001

Subthalamic nucleus deep brain stimulation (STN-DBS) is an efficacious treatment for selected individuals with advanced Parkinson's disease (PD) suffering from suboptimal motor control and motor fluctuations despite optimal peroral medication. After successful surgery, STN-DBS improves both motor and some non-motor symptoms and makes possible a reduction of the total dopaminergic medication load [1] thereby reducing pharmacological side effects [2,3]. However, over the years, the underlying disease processes continue unabated and lead to deterioration of non-motor and axial motor functions.

Source: Clinical Neurology and Neurosurgery - January 17, 2017 Category: Neurosurgery Authors: Radu Constantinescu, Barbro Eriksson, Yvonne Jansson, Bo Johnels, Bj örn Holmberg, Thordis Gudmundsdottir, Annika Renck, Peter Berglund, Filip Bergquist Source Type: research