Obesity Alters the Ovarian Glucidic Homeostasis Disrupting the Reproductive Outcome of Female Rats

Obesity constitutes a health problem of increasing worldwide prevalence related to many reproductive problems such as infertility, ovulation dysfunction, preterm delivery, fetal growth disorders, etc. The mechanisms linking obesity to these pathologies are not fully understood. Cafeteria diet (CAF) is the animal model used for the study of obesity that more closely reflects western diet habits. Previously we described that CAF induces obesity associated to hyperglycemia, reduced ovarian reserve, presence of follicular cysts and ovulatory impairments.

Source: The Journal of Nutritional Biochemistry - January 19, 2017 Category: Biochemistry Authors: MV Bazzano, DA Paz, EM Elia Source Type: research