Functional Connectivity When Detecting Rare Visual Targets in Schizophrenia

Individuals with schizophrenia demonstrate difficulties in attending to important stimuli (e.g., targets) and ignoring distractors (e.g., non-targets). We used a visual oddball task during fMRI to examine functional connectivity within and between the ventral and dorsal attention networks to determine the relative contribution of each network to detection of rare visual targets in schizophrenia. The sample comprised 25 schizophrenia patients and 27 healthy controls. Psychophysiological interaction analysis was used to examine whole-brain functional connectivity in response to targets.

Source: Psychiatry Research: Neuroimaging - January 16, 2017 Category: Psychiatry Authors: Amy M. Jimenez, Junghee Lee, Michael F. Green, Jonathan K. Wynn Source Type: research