Mitochondrial serine hydroxymethyltransferase 2 is a potential diagnostic and prognostic biomarker for human glioma

In the 1920s, Otto Warburg, a German physiologist, discovered that cancer cells, even under aerobic conditions, exhibit active glucose uptake and glycolysis, which has become widely known as the Warburg Effect [1]. Since then, energy metabolism in tumour tissue has become an important research direction for scholars. Abnormal metabolic change is an important feature of malignant tumours, and it also plays an important role in the occurrence and development of the tumour [2 –4]. The study of tumour metabolism may provide new indicators and intervention targets for the diagnosis and treatment of tumours.
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research