The role of nutrient sensing in the metabolic changes after gastric bypass surgery

In conclusion, RYGB surgery decreased body weight in both WT and α-gust–/– mice. Elevated plasma GLP1 and PYY levels might mediate this effect, although α-gustducin differentially affects several regulatory systems in the foregut and hindgut, tuning gut hormone release.

Source: Journal of Endocrinology - January 12, 2017 Category: Endocrinology Authors: Steensels, S., Lannoo, M., Avau, B., Laermans, J., Vancleef, L., Farre, R., Verbeke, K., Depoortere, I. Tags: Research Source Type: research