Intubation stress responses: Pre-anesthetic dexmedetomidine versus fentanyl in pre-eclamptic patients undergoing caesarean delivery: A prospective double blind randomized study

Conclusions Dexmedetomidine given over 10min before induction of general anesthesia significantly reduced the measured hemodynamic variables compared to baseline values. Dexmedetomidine successfully attenuated the intubation stress response and provided a significant hemodynamic stability more than fentanyl which given 3min before the induction of anesthesia in sever pre-eclamptic patients. Neither drug was associated with any harmful neonatal outcome. Pan African Clinical Trials Registry (PACTR201508001198128).
Source: Egyptian Journal of Anaesthesia - Category: Anesthesiology Source Type: research