Issue Information

Front cover: In recent years, sirtuin family genes have attracted attention because it has been reported that their activation extended lifespan in some animal species and yeast. Sirtuin family consists of several classes, and the majority of them encode NAD+‐dependent deacetylase. The arrow in this picture is called ‘hamaya,’ which is one of Japanese New Year's good luck charms. It is decorated with two ‘ema’s (wooden votive plaques) likened five‐membered ring of ribose with drawings of a crane and a turtle, common symbols of longevity in Japan. The arrow as a whole is mimicking the structure of NAD+, which is required for sirtuin's deacetylase activity. Designed by TRAIS Co., Ltd. (Kobe, Japan).

Source: Genes to Cells - December 31, 2016 Category: Genetics & Stem Cells Tags: Issue Information Source Type: research