CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells

In conclusion, our data suggest that CD36 plays an important role in H2O2-mediated lung injury and that the mechanism may involve CD36-dependent scaffolding of Fyn to the cell membrane to facilitate TRPV4 phosphorylation.

Source: AJP: Lung Cellular and Molecular Physiology - January 9, 2017 Category: Respiratory Medicine Authors: Suresh, K., Servinsky, L., Reyes, J., Undem, C., Zaldumbide, J., Rentsendorj, O., Modekurty, S., Dodd-o, J. M., Scott, A., Pearse, D. B., Shimoda, L. A. Tags: RESEARCH ARTICLE Source Type: research