Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis by downregulating iNOS, inducing anti-oxidative enzymes and arresting cell cycle progression

In this study, to better understand the role of colonic metabolites of NOB, we determined the anti-inflammation and anti-cancer effects of a mixture of NOB and its major metabolites (NOB-Met) at the concentrations equivalent to those found in colonic tissues of NOB-fed mice.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research