A Swedish Population-based Study of Adverse Birth Outcomes among Pregnant Women Treated with Buprenorphine or Methadone: Preliminary Findings

Conclusions: An increased frequency of the selected adverse birth outcomes was not observed with buprenorphine treatment during pregnancy. Twofold increased frequency of preterm birth 2.21 (1.11, 4,41) and congenital malformations 2.05 (1.08, 3.87) was observed in the methadone group, which may be partly explained by older average maternal age and differences in other measured and unmeasured confounders.
Source: Substance Abuse: Research and Treatment - Category: Addiction Authors: Source Type: research