Malleolar ulceration induced by Hydroxyurea therapy for chronic eosinophila

A 59-year-old African American female presented to a plastic surgery office in consultation for a very painful non-healing wound of her right lateral malleolus. An incisional biopsy was performed and ultimately a diagnosis of hydroxyurea-induced ulcer was concluded. Descriptions of this entity are rare in the surgical and wound care professional literature. This diagnosis does appear in the hematology/oncology literature; however, these practitioners may not be the first to examine a patient with the development of such an ulcer.
Source: Journal of the American College of Certified Wound Specialists - Category: Dermatology Authors: Source Type: research