In Silico Identification of Human Bile Salt Export Pump (ABCB11) Inhibitors Associated with Cholestatic Drug-Induced Liver Injury

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00744A, PaperLili Xi, Jia Yao, Yuhui Wei, Xinan Wu, Xiaojun Yao, Huanxiang Liu, Shuyan Li Drug-induced liver injury (DILI) is one of the major causes of drug attrition and failure. Currently, there is increasing evidence that direct inhibition of human bile salt export pump (BSEP/ABCB11)... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - January 5, 2017 Category: Molecular Biology Authors: Lili Xi Source Type: research