Strain-specific programming of prenatal ethanol exposure across generations

This study investigated the intergenerational consequences of prenatal exposure to low ethanol dose (1  g/kg) during gestational days 17–20, on ethanol-induced hypnosis in adolescent male F1 and F2 generations, in two strains of rats. Adolescent Long Evans and Sprague Dawley male rats were tested for sensitivity to ethanol-induced hypnosis at 3.5 g/kg or 4.5 g/kg ethanol dose using the loss of r ighting reflex (LORR) paradigm.
Source: Alcohol - Category: Addiction Authors: Source Type: research