CATH: an expanded resource to predict protein function through structure and sequence

This article describes developments to the CATH-Gene3D resource over the last two years since the publication in 2015, including: significant increases to our structural and sequence coverage; expansion of the functional families in CATH; building a support vector machine (SVM) to automatically assign domains to superfamilies; improved search facilities to return alignments of query sequences against multiple sequence alignments; the redesign of the web pages and download site.

Source: Nucleic Acids Research - January 2, 2017 Category: Research Authors: Dawson, N. L., Lewis, T. E., Das, S., Lees, J. G., Lee, D., Ashford, P., Orengo, C. A., Sillitoe, I. Tags: Database Issue Source Type: research