A multi species evaluation of the radiation dosimetry of [11C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor

The objectives of this study were to (1) establish a human dosimetry profile of [11C]erlotinib and (2) assess the consistency of calculated equivalent dose across species using the same dosimetry model.

Source: Nuclear Medicine and Biology - January 2, 2017 Category: Nuclear Medicine Authors: J. Ryan Petrulli, S øren B. Hansen, Galith Abourbeh, Maqsood Yaqub, Idris Bahce, Daniel Holden, Yiyun Huang, Nabeel B. Nabulsi, Joseph N. Contessa, Eyal Mishani, Adriaan A. Lammertsma, Evan D. Morris Source Type: research