Developing easy to perform routine MRI measurements as potential surrogates for cognitive impairment in MS

Multiple Sclerosis (MS) is a common cause of neurologic disability in young adults, diagnosed most frequently between the ages of 20 and 40 years [1]. Cognitive impairment (CI) has been recognized as an important feature of MS, affecting up to 65% of persons with MS (PwMS) [2,3]. CI, like physical disability in MS, can present differently in each person with MS, involving multiple cognitive domains, and these impairments are often undetected during routine clinical visits [4]. CI is often subtle in presentation, especially when mild, and difficult to assess in clinical settings and thus is often missed [5].
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research