HLA ‐DQA1 and HLA‐DQB1 allele diversity and its extended haplotypes in Madeira Island (Portugal)

This study shows, for the first time, high‐resolution allele frequencies of HLA‐DQA1 loci in Madeira Island (Portugal) and allows us to better understand and refine present knowledge on DQB1 variation, with the identification of several alleles not previously reported in this population. Estimates on haplotype profile, involving HLA‐A, HLA‐B, HLA‐DRB1, HLA‐DQA1 and HLA‐DQB1, are also reported.

Source: International Journal of Immunogenetics - November 30, 2016 Category: Genetics & Stem Cells Authors: H. Sp ínola, A. Lemos, A. R. Couto, B. Parreira, M. Soares, I. Dutra, J. Bruges‐Armas, A. Brehm Tags: Short Communication Source Type: research