Ultrasonically Assisted Cutting of Bio-tissues in Microtomy

Publication date: 2016 Source:Physics Procedia, Volume 87 Author(s): Dong Wang, Anish Roy, Vadim V. Silberschmidt Modern-day histology of bio-tissues for supporting stratified medicine diagnoses requires high-precision cutting to ensure high quality extremely thin specimens used in analysis. Additionally, the cutting quality is significantly affected by a wide variety of soft and hard tissues in the samples. This paper deals with development of a next generation of microtome employing introduction of controlled ultrasonic vibration to realise a hybrid cutting process of bio-tissues. The study is based on a combination of advanced experimental and numerical (finite-element) studies of multi-body dynamics of a cutting system. The quality of cut samples produced with the prototype is compared with the state-of-the-art.

Source: Physics Procedia - December 27, 2016 Category: Physics Source Type: research