Stability of endogenous GHB in vitreous humour vs peripheral blood in dead bodies

For the first time, the stability of GHB was tested in post-mortem peripheral blood and vitreous humor samples, collected from 22 dead bodies at two different times: at the external body examination at the place of death and then during autopsy.An ad hoc method for the detection and quantification of GHB in vitreous humor by gas chromatography coupled to mass spectrometry (GC-MS) was developed and validated, with a good linearity between 0.1 and 50 μg/mL (r2=0.991) and a precision and accuracy always better than 10% and an analytical recovery higher than 90%.

Source: Forensic Science International - December 25, 2016 Category: Forensic Medicine Authors: Francesco Paolo Busard ò, Giulio Mannocchi, Raffaele Giorgetti, Manuela Pellegrini, Giovanni Baglio, Simona Zaami, Enrico Marinelli, Simona Pichini Source Type: research