Enhancement of Working Memory and Task-Related Oscillatory Activity Following Intermittent Theta Burst Stimulation in Healthy Controls

We report here the findings from the first-ever investigation into the persistent cognitive and electrophysiological effects of intermittent TBS (iTBS) delivered to the left dorsolateral prefrontal cortex. In 19 healthy controls, active iTBS significantly improved performance on an assessment of working memory when compared with sham stimulation across a period of 40 min post stimulation. The behavioral findings were accompanied by increases in task-related fronto-parietal theta sychronization and parietal gamma band power. These results have implications for the role of more specialized stimulation approaches in neuromodulation.

Source: Cerebral Cortex - December 25, 2016 Category: Neurology Authors: Hoy, K. E., Bailey, N., Michael, M., Fitzgibbon, B., Rogasch, N. C., Saeki, T., Fitzgerald, P. B. Tags: Original Articles Source Type: research