The Project Of Another Low-Cost Metaphase Finder

The most popular and ‘gold standard’ phenomenon in Biological dosimetry is the appearance of dicentric chromosomes in metaphase in white blood cells. The metaphase finder is a tool for biological dosimetry that finds metaphase cells on slide glasses. The author and a software company were using new special software that was faster than conventional systems. A Nikon Eclipse Ni-E microscope with motorised X-Y stage, 4x objective lens and 1920 x 1024 pixels colour camera for hardware were used. The software uses mathematical morphology filters. The new system was compact and low-priced. And the remarkable point is, this system can be applicable not only to human blood, but also to non-human samples. The speed was 208–236 s per 5 x 20 mm area, while capturing 378 images, which achieved the aim of the project. The false-positive ratio achieved below 5% in some slides.

Source: Radiation Protection Dosimetry - December 22, 2016 Category: Radiology Authors: Furukawa, A. Tags: Paper Source Type: research