Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy

In conclusion, RUPP TH17 cells induced intrauterine growth restriction and increased blood pressure, AT1-AA, IL-6, and tissue oxidative stress when transferred to NP rats, indicating a role for autoimmune associated TH17 cells, to cause much of the pathophysiology associated with preeclampsia.

Source: AJP: Regulatory, Integrative and Comparative Physiology - December 21, 2016 Category: Physiology Authors: Cornelius, D. C., Amaral, L. M., Wallace, K., Campbell, N., Thomas, A. J., Scott, J., Herse, F., Wallukat, G., Dechend, R., LaMarca, B. Tags: Call for Papers Source Type: research