Resolving the cadherin –F-actin connection

Nature Cell Biology 19, 14 (2017).
doi:10.1038/ncb3457

Authors: Mitchell K. L. Han & Johan de Rooij
Cadherin adhesion complexes have recently emerged as sensors of tissue tension that regulate key developmental processes. Super-resolution microscopy experiments now unravel the spatial organization of the interface between cadherins and the actin cytoskeleton and reveal how vinculin, a central component in cadherin mechanotransduction, is regulated by mechanical and biochemical signals.

Source: Nature Cell Biology - December 22, 2016 Category: Cytology Authors: Mitchell K. L. Han Johan de Rooij Tags: News and Views Source Type: research