Computational simulation of passive leg-raising effects on hemodynamics during cardiopulmonary resuscitation

The passive leg-raising (PLR) maneuver has been used to predict fluid responsiveness [1], which is a crucial step for managing critically ill patients in terms of providing either preemptive action or proper treatment [2, 3]. However, more recently, the PLR maneuver is receiving much attention for its potential effectiveness during cardiopulmonary resuscitation (CPR) [4, 5]. According to the Frank-Starling relationship, if the heart is preload dependent and is fluid responsive, an increase in cardiac preload by recruitment of blood into the central circulatory compartment due to leg raising can increase stroke volume, which would also improve the outcomes of CPR [6].
Source: Computer Methods and Programs in Biomedicine - Category: Bioinformatics Authors: Source Type: research