TIMPs: versatile extracellular regulators in cancer
Nature Reviews Cancer 17, 38 (2017).
doi:10.1038/nrc.2016.115
Authors: Hartland W. Jackson, Virginie Defamie, Paul Waterhouse & Rama Khokha
A compelling long-term goal of cancer biology is to understand the crucial players during tumorigenesis in order to develop new interventions. Here, we review how the four non-redundant tissue inhibitors of metalloproteinases (TIMPs) regulate the pericellular proteolysis of a vast range of matrix and cell
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Hartland W. Jackson Virginie Defamie Paul Waterhouse Rama Khokha Tags: Review Source Type: research