The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia

Nature Reviews Cancer 17, 5 (2017). doi:10.1038/nrc.2016.112 Authors: Adam S. Sperling, Christopher J. Gibson & Benjamin L. Ebert Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal haematopoiesis of indeterminate potential (CHIP) to secondary acute myeloid leukaemia (sAML), MDS is distinguished by the presence of peripheral
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research