Chemotherapy: Less is more

Nature Reviews Cancer 17, 3 (2017). doi:10.1038/nrc.2016.151 Author: Anna Dart In response to maximum tolerated doses of chemotherapy, Chan et al. found that cancer-associated fibroblasts are activated through increased activity of signal transducer and activator of transcription 1 (STAT1) and nuclear factor-κB (NF-κB), leading to elevated levels and release of ELR+ chemokines.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research