Leukaemia: Don't let sleeping cells lie

Nature Reviews Cancer 17, 3 (2017). doi:10.1038/nrc.2016.150 Author: M. Teresa Villanueva In many patients with acute lymphoblastic leukaemia (ALL), most cells respond to chemotherapy but a minority show resistance and cause relapse with poor outcome. Using patient-derived xenograft models, Ebinger et al. identified a subpopulation of resistant and relapse-inducing cells with long-term dormancy and stemness
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research